The most widely accepted theory on aging supposes that the aging process is correlated with a gradual accumulation of errors in DNA.

TOO MUCH DEUTERIUM IN THE BODY

• It decreases your energy production.
• It reduces your ability to use energy.
• It deforms the three-dimensional structure of the proteins, fats, and carbohydrates you eat and your body makes.
• It doesn’t allow your DNA to fold properly and replicate.
• It changes the binding constants of your enzymatic reactions.
• It changes the pharmacokinetics and pharmacodynamics of your medicines, supplements, and other therapeutics.
• It may ultimately control who you are and how you respond to clinical treatments.
• Deuterium is coupled with DNA mutation and subsequent DNA damage.

WHY IS DEUTERIUM BAD?

Among many other bad things, it is about Aging

According to Kirk Goodall, a senior member of the technical staff with NASA, the number of irreversible errors in the DNA sequence is directly influenced by deuterium. The lower the deuterium concentration, the lower the frequency of irreversible errors in DNA structures.

WHAT IS THE LINK BETWEEN CANCER AND DEUTERIUM?

A transcript from an interview of Dr. Somlyai by Kriben Govender.

Dr. Gabor Somlyai graduated as a microbiologist in 1982 and received his Ph.D. He introduced hydrogen-deuterium regulating cancer growth to cancer research in 1990. Read on to learn how what we eat and drink can affect our deuterium levels, how cancerous cells are affected by the normal deuterium levels worldwide, and how we can reduce our risk of cancer.

Kriben: What Does The Name Albert Szent-Gyorgyi Mean To You?

Gabor: Albert was a Hungarian scientist who discovered vitamin C and its importance. He said that you have to go to a submolecular level to solve the cancer problem. We are close to a breakthrough in cancer research because this research started 50 years ago. He was clever enough to know that life is too complex and those big molecules can’t organize it. Where there are protons, you need an electron; if there is an electron, you need a positively charged proton.
Albert was a huge inspiration to me, and in 1976 I wrote that hydrogen is key in cancer development. After this, I kept this in my mind. Four years later, I was learning about pH entropy; at this time, heavy hydrogen was on my mind. I believed that deuterium was key in the molecular biology system.

Kriben: What is Deuterium?

Gabor: When we talk about heavy water, we think about nuclear power plants that use heavy water. It means that not two hydrogens bind to oxygen but two deuterium. Deuterium is heavy hydrogen. In the nucleus is a proton with mass number 1 and a neutron with mass number 1, so the deuterium mass number is 2. This is twice the mass of the nucleus of ordinary hydrogen. The deuterium gives you a different chemical reaction than it would if it wasn’t heavy water. If two hydrogens behave similarly, the chemical reaction does not count. In that case, it can count because the deuterium has different biochemical reactions. 

Kriben: Does Deuterium Replace Hydrogen?

Gabor: During evolution, there was a time when small bacteria could regulate life on a molecular level. But humans and animals are much more complex. Think about these:
• In the cell, there is a nucleus with a diameter of 100 micrometers
• Within the nucleus, there is DNA which is 1.8 meters if it were to be stretched out
• DNA is packaged in the nucleus, which, it is worth it noting, is only 100 micrometers
• It is so small, and it contains the 1.8-meter DNA
• It covers 25,000 genes
In one single cell, 2000 biochemical processes work perfectly.
Our body consists of 37 trillion cells, all of which are in harmony with each other and are fine. So the question is, how can life organize such a complex system? A cell can do this because it is organized and regulated on a sub-molecular level. This means the cells can modify the deuterium hydrogen ratio, and the molecules will do what the ratio says. Having deuterium in our body is normal, and it is also present in nature. We have deuterium in the Earth, in the ocean, in our food, and in surface water. The key issue is when someone gets cancer or another disease. The question is how we can cure or treat them and whether we can regulate the submolecular system. This is what we are researching.

Kriben: So you are trying to establish how the cells can regulate this ratio?

Gabor: Yes, we published the first paper in 1993, “Naturally occurring deuterium is essential to the normal growth rate of cells.” In this study, I checked how the cell culture behaved and grew with deuterium-depleted water. When I put it into the deuterium-depleted water the cell growth stopped. We also put human breast cancer into mice and replaced their water with deuterium-depleted water. This eliminated the tumor growth in the mice. So this data suggested that cancer required the deuterium to keep and manage the tumor cell growth in mice. When the growth hormone binds to the membrane that will stimulate the sodium hydrogen, the pH increases as the hydrogen concentration decreases in the cell. This is a signal for the cell to multiply, but no one could explain the signal. But we said that when the growth hormone binds to the membrane and stimulates the hydrogen transport system, the deuterium level will increase in the cell. The membrane will discriminate between the two hydrogens. If the cell has cancer cells, then the cell will multiply. This is the accelerator.

The question is, where is the brake? The brake system is in the mitochondria. When we eat food, we burn it into carbon dioxide and metabolic water. Everyone, every day, produces deuterium-depleted water in the body. This is what healthy cells do. If we compare the cancer cells, what is the only difference? The mitochondria. In healthy cells, the mitochondria are working properly. They can produce deuterium-depleted metabolic water. But we know that the mitochondria do not work properly with cancerous cells. The cancerous cells cannot produce deuterium-depleted metabolic water. The damaged mitochondria in the damaged cells allow the deuterium and hydrogen ratio to get out of balance, and cancer will grow.

Kriben: What Are Mitochondria?

Gabor: Within the cell, there are many organelles. One of them is the mitochondria. It produces ATP when we eat the energy that is stored in food. The cells can use this as an energy source for other chemical reactions. The mitochondria is covered with a double membrane, and there are the ATPase nanometers, a group of enzymes on the membrane.

This spins 9000 times per minute, and the hydrogen ion fuels it. It is essential for the mitochondria and the ATPase to discriminate against any deuterium in preference for hydrogen as it will use it as fuel for this process.
The other key issue with the mitochondria is what is the carbon source. What we eat will determine the deuterium level of the metabolic water. When I went to the supermarket, I started looking at different foods, including:
• Cottage cheese
• Butter
• Sugar

I took the water out of each of them and saw the deuterium content. It turns out that the carbohydrate contains 150 ppm. The PPM means that there is 150 deuterium per million parts. When we checked the fat level (butter and cottage cheese), it was MUCH lower at 118ppm. When we eat a lot of carbohydrates, the mitochondria produce deuterium water, and this concentration will be higher than if we were to consume fat. People say that fat is very harmful and that 60% of your food intake should be carbohydrates, but our deuterium level would be higher than someone else’s with a diet rich in fat. It was normal to consume all this fat back in the day, and now, many foods are low-fat.

What we eat, how we move, and how we think can modify the deuterium level in the body. The cell membrane can increase the deuterium level; the mitochondria will push down the level. It is a game.

Kriben: Are you saying that the dietary factors of carbohydrates vs fats will have a major impact on the cells ability to deplete deuterium and that carbohydrates have a higher deuterium load which may result in the cells having a higher deuterium content whereas consuming fats would lower this deuterium content?

Gabor: Yes.

Kriben: Could you also talk about the difference between the TCA Cycle vs Pentose Phosphate? Is there a difference between whether metabolism happens in one pathway vs. another?

Gabor: All the biochemical processes depend on and modify each other. The deuterium hydrogen ratio should be at the end or the beginning of this process. We have run studies where we labeled glucose to carbon 13, the glucose was given to the cells, and then we separated the molecules. The liquid map of the carbon 13 and the different molecules went with the glucose. That was where we could find big differences between normal water and deuterium depleted water. We can say that the deuterium level can modify ALL of the biochemical processes in our bodies and cells.

Kriben: What Does Deuterium Do To The Mitochondria?

Gabor: We ran a study with athletes. One group of athletes consumed 105 ppm DDW reduced from their normal 150 DDW for 44 days, while the others drank regular water.

There was a test at the beginning and end of the study. There was a huge difference between the two groups. The group consuming deuterium-depleted water had their lactic acid appear later during the test. This showed that the mitochondria worked more efficiently. The oxygenation of their glucose was much better. This suggested that the lower deuterium level can help the mitochondria and ATPase synthesize ATP more effectively, AND it has enough oxygen to oxygenize carbohydrates.

The glucose level did not change during the first 5 minutes of the loading test. It reduced the glucose, suggesting that the oxygenation could use up the glucose more properly. The ATPase is spinning 9,000 times per minute, and deuterium can damage the mitochondria and the ATPase. That is why deuterium-depleted water was very useful to these athletes.

Kriben: What is The Normal Range of Deuterium Levels?

Gabor: The normal deuterium level of water is 155 ppm in the ocean, in Europe the water is 145 ppm, and if you go to the north or south pole it’s lower. If we look at the millimole instead of the ppm in our bodies, the deuterium level is 6x higher than the amount of calcium in our blood and 9x more elevated than the magnesium level in our blood. Since the 1930’s when deuterium was discovered, they found that 6,600/1 was the ratio of hydrogen and deuterium and everyone wanted to ignore it because 6,600/1 is not that big of a number…..But if you check the millimole, 12 millimoles is extremely high in a living organism. Deuterium is essential and important, but having too much of it can be bad.

Over a lifetime, it’s important to wonder what the deuterium level in the body is. If it’s 150 ppm, we may have a higher chance of getting cancer than if it was 140 ppm.

“We have recently run testing on water samples in Australia coming from taps, bottled water, and they are all around 155 ppm. I think that geographically Australia is the canary in the coal mine. A whole region has a high deuterium level. We are seeing a whole lot of health issues in this country. Hopefully, people will consider alternatives in water and something lower in deuterium. – John Hardgrave”

Kriben: How is Cancer Related to Mitochondria, and How Does Deuterium Influence the Situation?

Gabor: It takes 4-5 years for that single cell to diagnose the tumor. By that time, the tumor size may be 1 centimeter. It was not that “Yesterday I was healthy, and today I got cancer.” That cancer started many years ago….. It is also a big mistake to think the cancer is gone when the tumor is removed and you believe you are healthy. Within those 4-5 years, tumor cells can leave the primary tumor, and those cells can survive. We can never say that the tumor was removed in time; we can only remove the tumor in the early stage or late stage but never in time.

We can modify the probability of having cancer or not throughout our lifetime. You need to find the mutation in the genome and the genes in the tumor development. The other idea is that the metabolic system is responsible for cancer growth. We can prove that gene mutations can increase the risk of cancer. The higher deuterium levels can cause mutations, so when the DNA replicates, the deuterium can increase the mutation rate and increase the chance of mutation in a region.

Kriben: What Can We Do During our Lifetime to Reduce the Risk of Cancer?

Gabor: Lower deuterium levels should reduce the risk of cancer. For healthy people, consuming deuterium-depleted water for 3-4 months every year would be great because we can reduce these deuterium levels. The tumor cells cannot tolerate this type of change. Because of the damaged mitochondria and processes in the cancer cells, they require deuterium. Those cancer cells can be eliminated by giving deuterium depleted water since they cannot handle this change. When we reduce the deuterium level from the outside, we are diluting the normal level in our bodies…

We have a database of 171 cancer patients who were operated on and then consumed deuterium-depleted water to prevent relapse. Our data shows that we only lost 11 of those patients. While 7 of the patients that died consumed deuterium depleted water, had a break, and drank again for a couple of months, they then stopped altogether, and 5 years later, they passed away.

That means that we can largely prevent cancer relapse for those who returned and repeated this process every year. If we consume this water, the cancer cells cannot tolerate them and will die off. We can reduce the risk of cancer AND relapse of cancer.

Kriben: I am stunned that I have never heard of this type of information broadcast sooner. If you have been working on this for over 30 years, I am wondering why this information is not more widely talked about. Just in Australia alone, 1 in 2 people will develop cancer. I hope this message gets to the people on the promise that this information holds. Not only to cure but as a preventative measure to have people live great lives to live cancer-free.

Gabor: The pharmaceutical industry is going to find the molecules. They are seeking the genes responsible for cancer. They are spending billions of dollars to cure people. I understand that people are skeptical about why deuterium-depleted water would be good for curing cancer, but the time has come. The price of cancer drugs is high, but the efficiency is low. Even with the drugs, people are dying. Science must find the reason and figure out what is happening with cancer.

In the long term, we need to study different concentrations of deuterium-depleted water as a drug. This is the only way that people will be able to get it. We must educate the oncologists on using deuterium-depleted water in their therapy. We have to integrate deuterium depletion into the existing treatment. This will help increase the chance of survival.

Overall we need to pay attention to the deuterium levels in the water for our families. Be careful of what they are consuming.

Kriben: This information is also pertinent to gut health. There are mitochondria in all of the gut cells. These gut cells replenish themselves every 24-48 hours. The mitochondria must function properly. If the mitochondria aren’t working properly and the gut lining isn’t functioning properly, it could lead to many problems like a leaky gut.

So try to source out the lowest deuterium-depleted water you can find. This will starve the cancer cells and prevent them from growing. This will also make your gut happy because the gut cells are functioning more efficiently. Consuming more good fats rather than carbohydrates will put you at an advantage from the start. Focus on healthy fats to lower your deuterium content.

Share this with a friend that would benefit from this information.

Initially published on https://www.h2-4you.com/what-is-the-link-between-cancer-and-deuterium/

ALWAYS REMEMBER

The presence of deuterium in these enzymes slows DNA replication, causes transcription errors, and hinders DNA repair.

Less deuterium, better Mitochondrial functions.

Defective mitochondria due to limited water production and insufficient deuterium depletion may be common central metabolic events during cancer development in the pancreas and other organs.

The lower the deuterium concentration, the lower the frequency of the irreversible errors in DNA structure.

DID YOU KNOW?

At the millimole instead of the ppm in our bodies, the deuterium level is 6x higher than the amount of calcium in our blood and 9x more elevated than the magnesium level in our blood.

It takes 4-5 years for that single cell to diagnose the tumor. By that time, the tumor size may be 1 centimeter. Within those 4-5 years, tumor cells can leave the primary tumor, and those cells can survive. It was not that “Yesterday I was healthy, and today I got cancer.” That cancer started many years ago. It is also a big mistake to think the cancer is gone when the tumor is removed, and you believe you are healthy. We can never say that the tumor was removed in time; we can only remove the tumor in the early stage or late stage but never in time.

The higher deuterium levels can cause mutations, so when the DNA replicates, the deuterium can increase the mutation rate and increase the chance of mutation in a region.

Try to source out the lowest deuterium-depleted water you can find. This will starve the cancer cells and prevent them from growing and will also make your gut happy because the cells are functioning more efficiently. Consuming more good fats rather than carbohydrates will put you at an advantage from the start. Focus on healthy fats to lower your deuterium content. Share this with a friend that would benefit from this information.

In 1964, one of the greatest revelations in biology was taken shape by Paul D. Boyer, a molecular biologist with UCLA. He discovered that tiny protein nano-motors within the mitochondria, sitting at the end of the Electron Transport Chain (ETC), bore the final burden for creating ATP. Boyer christened it “ATP Synthase”. This protein assembly, spinning at 9000 RPM, has the structure and function of a mechanical motor, complete with rotor, stator and magnetic field. It would be another 40 years, and the turn of the millennium, before deuterium’s effect on ATP Synthase would be uncovered.

By the early 1960’s, deuterium, although a hydrogen isotope, was something altogether “different” biochemically and biophysically. Deuterium is twice the mass of protium due to the addition of a neutron absent from normal hydrogen. No other element has such an extreme difference in mass among its isotopes. Nevertheless, understanding how deuterium functions at the cellular level were yet to be discovered.

Ten years later, in 1974, again at Argonne National Labs, British scientist T.R. Griffiths, at the 2nd International Conference on Stable Isotopes, proposed the theory that deuterium might be the primary cause of aging. In Possible Roles of Deuterium in the Initiation and Propagation of Aging and Other Biochemical Mechanisms and Processes, he states, “Deuterium adversely affects the shape of enzyme molecules involved in DNA replication.”

He observed that deuterium is more electronegative than hydrogen, twice as heavy, and has different atomic binding properties than normal hydrogen (protium), interfering with DNA replication. When DNA repair enzymes contain deuterium in a position reserved for protium, they can potentially participate in an error reaction, thereby compromising DNA replication and repair. The following year, in 1975, J.D. Gleason and I. Friedman, replicating the Russian findings on plant growth, published the first American study on using deuterium-depleted water (DDW) to increase the growth of grains. This small but significant publication in NATURE magazine paved the way for a new generation of scientists to understand the function of deuterium in the biology of living things.

How Deuterium Hurts Us 

Author: John Hardgrave (“H2 for You”). is also the principal in a wellness organization called “Flower of Light,” whose mission is to improve clients’ health and well-being. 

Could the very water you drink make you sick?

Deuterium. It may be the first you’ve heard of this substance. What is it, and why is it in the water we drink and the foods we eat? Deuterium is a stable isotope of hydrogen. Everything is made up of atoms. These tiny things join together to form molecules that make up every physical object in the world. Now, all of these atoms are made up of protons, neutrons, and electrons. Isotopes are atoms of the same element (water is an element) but with different numbers of neutrons, causing them to have another atomic weight.
Deuterium has an extra neutron that makes it “heavier” than the hydrogen part of our water. This makes it an “isotope”. So how does this isotope hurt our bodies?

Think of your body like a car

Your mitochondria are the “engine” that makes your car move down the road. Your mitochondria need water to work like your car’s engine needs gas to run. Now, imagine if there were little wrenches in the gas you put in your car. What would happen to your car’s engine if you threw a wrench in it? Would it break apart, right? Well, that’s what happens to your body’s mitochondria when you drink deuterium water. The deuterium is too “heavy” for your mitochondria to use and destroys your cells’ engines. When you destroy the engines of your cells, you create an environment that is optimal for disease and sickness to occur.
Characteristics of too much deuterium in the body:
• It decreases your energy production.
• It reduces your ability to use energy.
• It deforms the three-dimensional structure of the proteins, fats and carbohydrates you eat and your body makes.
• It doesn’t allow your DNA to fold and replicate properly.
• It changes the binding constants of your enzymatic reactions.
• It changes the pharmacokinetics and pharmacodynamics of your medicines, supplements and other therapeutics.
• It may ultimately control who you are and how you respond to clinical treatments.